Header menu link for other important links
X
Appraisal on: Tablet coating and its outcome with complementary sprouting technology
O. Bagade M., , N. Nemlekar A., P. Kharat P., A. Shete M., M. Vanave D.
Published in Research Journal of Pharmaceutical, Biological and Chemical Sciences
2014
Volume: 5
   
Issue: 5
Pages: 298 - 315
Abstract
Tablet coating is the key step involved in the manufacturing of tablets having controlled release, delayed release profiles. The tablet coating have number of advantages like masking odor, taste, color of the drug, providing physical and chemical protection to drug, Protecting drug from the gastric environment. Tablets are usually coated in horizontal rotating pan with coating solution is either directly poured or sprayed on to them. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form. Recent trends in tablet coating focuses on overcoming disadvantage of solvent based coating. This review concerns with the coating process, equipments involved, coated tablets evaluation and specialized coating techniques. Tablets are usually coated in horizontal rotating pans with the coating sprayed onto the free surface of the tablet bed. Tablets must have a coating mass that lies within a prescribed range with very little inter-and intra-tablet coating variability. Using the Discrete Element Method (DEM) tablet coating can be simulated on the computer. Simulation data provide the position, velocity and orientation of each tablet within the coater allowing accurate measurements of the time and orientation that each tablet spends exposed to the coating spray.
About the journal
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
PublisherResearch Journal of Pharmaceutical, Biological and Chemical Sciences
ISSN09758585
Open AccessNo