The present work aims at evaluating material properties of femur bone in Indian subjects, so as to facilitate further study of total hip joint and replacement of joint in Indian subjects. These properties are required to be determined before F.E.M. analysis of indegenised hip joint to study its stability in the bone. The shaft of the artificial hip joint is fixed in femur bone in its proximal and medial cancellous portion. Study of The interaction of metallic joint with bone material necessitates the mechanical properties of bone to be evaluated. These properties were derived from femur bones of Indian donors. This experimental study aims at determining orthotropic behavior of cancelleous portion of cadeveric femur bone. This property may prove useful in studies related to total hip joint replacements. This study attempts at providing comprehensive items of mechanical properties of cadeveric cancellous distal femur, through series of mechanical tests, which comprised of tensile testing, compression testing, shear testing. The specimens were extracted from normal Indian donors. Series of experimental data stated here include tensile strength, compressive strength, and yield strength, modulus of elasticity, torsional strength and shear modulus, which can reflect the complex material behavior of femur bone. The experimental results establish orthotropic nature of femur bone as expected. © Society for Biomaterials and Artificial Organs (India).