A green and eco-friendly one-pot, four-component synthesis of methyl 6-amino-5-cyano-4-aryl-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates in water catalyzed by titanium dioxide (TiO2) is described. Reaction protocol is advantageous over previous methods owing to short reaction time, simple operating procedure, higher yields of product, simple work up procedures affording desired product in good to excellent yield.

Anuruddha Rajaram Chabukswar

School of Pharmacy

Pharmacy

Shahebaaz Pathan K.

Satish Deshmukh

Santosh Chhajed S.

Jaiprakash Sangshetti

MIT-World Peace University (MIT-WPU) is a top educational institute located in Pune, India. It is recognized within&nbsp;UGC under Government of Maharashtra Act No. XXXV 2017.&nbsp;

It is part of the MIT group of institutions (established in 1983) which covers 10+ campuses across India and has more than 50,000+ students enrolled across various disciplines at a given point of time. The institute houses 15 schools ranging from Engineering &amp; Technology, Design, Pharmacy, Commerce, Governance among others. It offers undergraduate, postgraduate and PhD programs among different disciplines.&nbsp;

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MIT World Peace University

Chemical Data Collections

Green Synthesis Of Methyl-6-Amino-5-Cyano-4-Aryl-2,4-Dihydropyrano[2,3-C]Pyrazole-3-Carboxylates using Dimethyl Acetylene dicarboxylate

Journal	Data powered by TypesetChemical Data Collections
Publisher	Data powered by TypesetElsevier B.V.
ISSN	24058300
Open Access	No