This paper discusses the suitability of HFC-161 over other refrigerants. Apart from having zero ODP and GWP value of 12,HFC-161 refrigerant can prove a promising alternative to HCFC-22 and various other HCFC refrigerants facing the fate ofphase out. Various results are obtained on the basis of COP, discharge temperature, cooling capacity and powerconsumption. The general finding shows that HFC-161 refrigerant gives better COP, increased refrigeration effects andlower discharge temperatures. The flammability of HFC-161 needs to be addressed while using in air conditioner. A 1.5 TRcapacity DC inverter operated air conditioner is to be tested in psychometric test laboratory for Capacity rating and Powerconsumption test.