Special Issue-3, (April 2014) Abstract A centrifugal pump is a rotodynamic pump that uses a rotating impeller to increase the pressure of a fluid. The fluid enters the pump impeller along or near to the rotating axis and is accelerated by the impeller, flowing radially outward into a diffuser or volute chamber (casing), from where it exits into the downstream piping. Computational fluid dynamics deals with fluid mechanics that uses numerical methods and algorithms to solve and analyze problems that involve fluid flows. Computers are used to perform the calculations required to simulate the interaction of liquids and gases with surfaces defined by boundary conditions. However, since experiments are limited by the facilities and the costs, computational fluid dynamics is also used to complement the experiments. The lead times and costs of new designs may then be substantial reduced. To use the computational fluid dynamics the various tools are available among them few are commercial and few are open source. For commercial tools one has to pay a lot while for open source tool it is free ware. In this project work the analysis of centrifugal pump in commercial tool i.e. ANSYS and in open source i.e. Open FOAM is carried out. Numerical solutions of the rotor-stator interaction of Centrifugal Pump using ANSYS CFX and OpenFOAM-1.5-dev were investigated.