A simple, economical, precise and accurate method for simultaneous determination of Atenolol (ATE) and Lercanidipine Hydrochloride (LER) in combined dosage form has been developed. The first method is based on Ratio Derivative (Method A) and second method is based on Dual Wavelength (Method B). The amplitudes 266.98 nm and 386.97 nm wavelength were selected to determine ATE and LER respectively, by method A. In method B, two wavelengths were selected for each drug in a way so that the difference in absorbance is zero for another drug. At wavelengths 234.01 nm and 238.66 nm Lercanidipine have equal absorbance therefore these two wavelengths were used to determine ATE and on similar basis 253.33 nm and 286.07 nm were selected to determine LER in combined formulation. The drugs obey Beer's law in the concentration range of 25-125 $\mu$g mL-1 for ATE and 5-25 $\mu$g mL-1 for LER by the method A and 50-90 $\mu$g mL-1 for ATE and 10-18 $\mu$g mL-1 for LER by the method B. The % assay of LER and ATE was found to be in the range 99.98 - 101.12 % by the proposed methods. Recovery was found in the range of 98.4 - 101.0 % for both analytes by both methods. The results of analysis have been validated statistically and recovery studies confirmed the accuracy and reproducibility of the proposed methods which were carried out by following ICH guidelines.