A simple, economical, precise and accurate method for simultaneous determination of Drotaverine (DRT) and Aceclofenac (ACE) in combined dosage form has been developed. The first method is Ratio Derivative spectroscopy method (Method A) in which ratio derivative amplitudes were measured at selected wavelengths. Second method is Area under Curve Spectrophotometry (Method B). The amplitudes at 330.13 nm and 228.06 nm in the Ratio derivative spectra were selected to determine DRT and ACE, respectively and wavelength ranges 299-305 nm and 270-277 nm were selected to determine DRT and ACE, respectively by AUC method in methanoldistilled water. Beer's law is obeyed in the concentration ranges of 4-20 $\mu$g mL-1 and 5-25 $\mu$g mL-1 for DRT and ACE, respectively in method A while 4-24 $\mu$g mL-1 and 5-30 $\mu$g mL-1 by DRT and ACE, respectively in method B. The % assay for commercial formulation was found to be in the range 99.48 - 100.01 % for DRT and 99.52 - 99.89 % for ACE by the proposed methods. Recovery was found in the range 99.18-100.10 for DRT and 99.52 - 101.09% for ACE by ratio derivative spectroscopic method and 99.82 - 101.12% for DRT and 99.73-101.09% for ACE by AUC method for both the Formulations. The results of analysis have been validated statistically and recovery studies confirmed the accuracy and of the proposed methods which were carried out by following ICH guidelines.