A simple, economical, precise and accurate method for simultaneous determination of Dutasteride (DUTA) and Tamsulosin (TAM) in combined dosage form has been developed. The first method is first order Derivative spectroscopy method (Method A) in which derivative amplitudes were measured at selected wavelengths. Second method is Area Under Curve Spectrophotometry (Method B). The amplitudes at 247.67 nm and 232.60 nm in the first order derivative spectra were selected to determine DUTA and TAM, respectively and wavelength ranges 237.13-238.25 nm and 222.50-223.62 nm were selected to determine DUTA and TAM, respectively by AUC method in methanol. Beer's law is obeyed in the concentration ranges of 10-50 $\mu$g mL-1 and 8-40 $\mu$g mL-1 for DUTA and TAM, respectively in method A while 5-25 $\mu$g mL-1 and 4-20 $\mu$g mL-1 by DUTA and TAM, respectively in method B. The % assay for commercial formulation was found to be in the range 99.24 - 100.09 % for DUTA and 99.89 - 101.12 % for TAM by the proposed methods. Recovery was found in the range of 99.60 - 99.99 % for DUTA and 100.02 - 101.09% for TAM by first order derivative spectroscopic method and 99.30 - 101.12% for DUTA and 99.52-101.25% for TAM by AUC method for both the Formulations. The results of analysis have been validated statistically and recovery studies confirmed the accuracy and reproducibility of the proposed methods which were carried out by following ICH guidelines. The proposed methods were applied successfully to determine uniformity of contents in commercial capsule and tablet formulations.