A simple, economical, precise and accurate methods for simultaneous determination of Dutasteride (DUTA) and Tamsulosin (TAM) in combined tablet and capsule dosage form has been developed. The first method is based on Ratio Spectra Derivative (Method A) and second method is based on Dual Wavelength Spectrophotometry (Method B). Methanol was used as solvent for both the methods. The amplitudes 250 nm and 234.20 nm in the second derivative of the ratio spectra were selected to determine DUTA and TAM, respectively. In the second method i.e. Dual method in which two wavelengths were selected for each drug in a way so that the difference in absorbance is zero for another drug. At wavelengths 221.43 nm and 227.47 nm tamsulosin have equal absorbance therefore these two wavelengths were used to determine Dutasteride (DUTA) and on similar basis 272.35 nm and 276.05 nm were selected to determine Tamsulosin (TAM) in combined formulation. The drugs obey Beer's law in the concentration range of 5-25 TimesNewRoman, Italic.-1.c01g mL-1 for DUTA and 4-20 TimesNewRoman, Italic.-1.c01g mL-1 for TAM by both the methods. The methods were validated with respect to linearity, precision and accuracy. The results of analysis have been validated statistically and recovery studies confirmed the accuracy and reproducibility of the proposed methods which were carried out by following ICH guidelines. The proposed methods were applied successfully to determine uniformity of contents in commercial capsule and tablet formulations.