In this paper, the effect of approach angle, feed, depth of cut and nose radius on cutting force components were investigated. The experiments were conducted on PSG 124 lathe machine using carbide coated cutting tools on material hardened EN9. The orthogonal array of L-16 was used for optimization of tests. Cutting forces generated during lathe turning operation were measured using three axis lathe tool dynamometer. Statistical regression analysis method was applied to investigate the maximum cutting force generated and which was found at an approach angle = 450, feed = 0.3 mm, depth of cut = 1 mm and noseradius = 0.8 mm. Static and fatigue analysis has been carried out numerically by considering different forces acting on lathe spindle. Results of this analysis show, the present design of spindle is safe.